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Effects of Doxazosin Gastrointestinal Therapeutic System on Ambulatory Blood Pressure and Cardiovascular Risk Factors in Uncontrolled Hypertensive Patients

Last updated on February 18, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Brescia, , 25123 Italy
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Hypertension
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Eligible subjects were males or females ≥18 years of age with a diagnosis of primary
essential hypertension and currently taking 1 or 2 individual antihypertensive agents

- Dosing for entry antihypertensive medication was at the accepted efficacious dose or
the maximum tolerated dose and had to be stable for at least 4 weeks prior to study
entry

- Subjects were required to have clinic sitting DBP ≥95 and ≤110 mmHg and SBP ≥140 and
≤180 mmHg as an average of 3 readings on their current antihypertensive therapy at
visits 1 and 2

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

Exclusion criteria included, but were not limited to:

- Subjects taking antihypertensive medications for other indications (i.e. arrhythrma,
unstable angina, CHF, etc.)

- Orthostatic hypotension, defined as a decrease of at least 20 mmHg systolic or 1OmmHg
diastolic pressure between sitting and standing blood pressures after 2 rmnutes, or
known fluid depletion.

NCT00646841
Pfizer
Completed
Effects of Doxazosin Gastrointestinal Therapeutic System on Ambulatory Blood Pressure and Cardiovascular Risk Factors in Uncontrolled Hypertensive Patients

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Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

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FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

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