- Diagnosis of schizophrenia or schizoaffective disorder
- Outpatients for at least 3 months on treatment with sulpiride, olanzapine, quetiapine,
or risperidone and at least a partial beneficial response to typical antipsychotic
treatment including for the current episode
- Partial improvement in symptoms that justified a switch to ziprasidone
- Diagnosis of major depression or occurrence of moderate depressive symptoms
- Resistance to conventional antipsychotic drugs
- Treatment with other drugs such as antiseizure medications, antipsychotics,
antidepressants, or mood stabilizing agents that might interfere with the assessement
of the efficacy of ziprasidone