Eligibility criteria
Condition
Non-Small Cell Carcinoma, Neoplasm Metastasis
Sex
Females and Males
Age
18 + years
Inclusion criteria
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- Histologically documented advanced cancer, Eastern Cooperative Oncology Group (ECOG)
0-1;
- Platelets > 100,000, ANC > 1500;
- Ccr > 60 or serum creat.
- Non-small cell cancer cohort:
- Eastern Cooperative Oncology Group (ECOG) 0-2, prior platin, regimen
- HgA1C
Exclusion criteria
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- Active Central Nervous System (CNS) metastases;
- prior IGF1-R targeted therapy
- Any history of unstable angina, myocardial infarction or symptomatic congestive heart
failure.