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Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors

Last updated on March 15, 2019

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Study Location
Pfizer Investigational Site
Los Angeles, California, 90095 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Advanced Cancer, Advanced Solid Tumors
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Histologically or cytologically confirmed advanced solid tumors relapsed or refractory
to standard therapy or for whom no standard therapy exists.

- ECOG Performance Status of 0 or 1;

- Total IGF-1 level ≥100 ng/ml;

- ECOG Performance Status of 0 or 1

- Adequate bone marrow, renal, and hepatic function

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Concurrent treatment with any antitumor agents with the exception of LHRH agnosits for
prostate cancer patients

- Treatment with any other investigational therapy within 4 weeks prior to study
treatment

- Major surgery within 4 weeks of study treatment

- Prior treatment that may increase the risk of cardiac complications

- Ongoing cardiac dysrhythmias of NCI CTCAE Grade 2 or greater

- Significant active cardiac disease, including hypertension that cannot be controlled
by medications

- Greater than three (3) prior lines of cytotoxic therapy;

- Active infection

- Prior IGF-IR targeted therapy;

NCT00729833
Pfizer
Terminated
Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors

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Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

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Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

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