- Heterozygous familial hypercholesterolemia, ages 6-15, LDL greater than 4 mmol/l
- Active liver disease or hepatic dysfunction, or persistent elevations of serum
transaminases exceeding three times the upper limit of normal (ULN).
Female of childbearing potential who is not using adequate contraceptive measures or any
female who is pregnant or breastfeeding. Any female who becomes pregnant during study
participation will be immediately discontinued from treatment and counseled appropriately
about the in utero exposure.
Known hypersensitivities to HMG-CoA reductase inhibitors