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A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

Last updated on March 14, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Huntsville, Alabama, 35801 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Rheumatoid Arthritis
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- The patient has a diagnosis of Rheumatoid Arthritis based on the American College of
Rheumatology (ACR) 1987 Revised Criteria.

- The patient has active disease as defined by both >=4 tender or painful joints on
motion and >= 4 joints swollen; and either an erythrocyte sedimentation rate (ESR) >
28 mm or a C-reactive protein (CRP) concentration > 7 mg/dL.

- Patient had an inadequate response to at least one disease modifying antirheumatic
drug (traditional or biologic) due to lack of efficacy or toxicity.

- Patient must remain on at least one background traditional disease modifying
antirheumatic drug.

- No evidence of inadequately treated latent or active infection with Mycobacterium
tuberculosis.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Blood dyscrasias including confirmed: Hemoglobin blood cell count

- History of any other rheumatic autoimmune disease other than Sjogren's syndrome.

- No malignancy or history of malignancy.

- History of infection requiring hospitalization, parenteral antimicrobial therapy, or
as otherwise judged clinically significant by the investigator, within the 6 months
prior to the first dose of study drug.

NCT00856544
Pfizer
Completed
A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

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[email protected]

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Contact a representative by phone, email, or visiting the study website. Please see the references below:

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Pfizer Clinical Trials Contact Center

1-800-718-1021

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