Eligibility criteria
Condition
Type 2 Diabetes Mellitus
Sex
Females and Males
Age
18-70 years
Inclusion criteria
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- Male and/or female patients (females will be women of non-childbearing potential) with
an historical diagnosis of type 2 diabetes mellitus, who are currently being treated
with metformin at a dose at or near maximum.
- Hb A1c between 7-10%.
- Fasting C-peptide >0.4 nmol/L.
Exclusion criteria
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- History of clinically significant chronic conditions other than T2DM not well
controlled by either diet or medications.
- Patients with pancreatitis or considered a high risk for pancreatitis.
- History of contraindications to metformin therapy.
- Previous treatment with an approved or investigational GLP 1 mimetic.