A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery


Last updated date
Study Location
Pfizer Investigational Site
Paris Cedex 13, , 75651, France


Contact a representative by phone, email, or visiting the study website. Please see the references below:

By phone

Pfizer Clinical Trials Contact Center


By email


[email protected]

Call Now

Eligibility Criteria
The disease, disorder, syndrome, illness, or injury that is being studied.
Smoking Cessation
Females and Males
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion Criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Smokers motivated to stop smoking scheduled for elective surgery

Exclusion Criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Current or recent depression

- Current or recent suicidal ideation

- Uncontrolled or unstable clinically significant medical condition


Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative

Pfizer Clinical Trials Contact Center


[email protected]


Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

Based on your search, you may also be interested in

Smoking CessationVarenicline Observational Investigation In The Cessation of Smoking
  1. Alleur,
  2. Beerse,
  3. Braine le Comte,
  4. Bruxelles,
  5. Bruxelles,
  6. Bruxelles,
  7. Deinze,
  8. Edegem,
  9. Genk,
  10. Gent,
  11. Habay-la-Neuve,
  12. Halen,
  13. Jette,
  14. Kortessem,
  15. Leuven,
  16. Libramont-Chevigny,
  17. Liege,
  18. Moerkerke,
  19. Monceau-sur-Sambre,
  20. Moorsel,
  21. Namur,
  22. Rijkevorsel,
  23. Vedrin,
  24. Vilvoorde,
  25. Yvoir,
  26. Zedelgem,
  27. Holargos, Athens
  28. Ilisia, Athens
  29. Marousi, Athens
  30. Herakleion, Crete
  31. Exohi, Thessaloniki
  32. Alexandroupoli,
  33. Ioannina,
  34. Kavala,
  35. Larissa,
  36. Thessaloniki,
  37. Budapest,
  38. Budapest,
  39. Eger,
  40. Erd,
  41. Farkasgyepu,
  42. Hatvan,
  43. Nyiregyhaza,
  44. Siofok,
  45. Szombathely,
  46. Zalaegerszeg,
  47. Cerknica,
  48. Domzale,
  49. Jesenice,
  50. Kranj,
  51. Ljubljana,
  52. Maribor,
18 Years+
Smoking CessationA Phase I Study to Evaluate the Pharmacokinetics of Multiple Doses of Varenicline in Healthy Adolescent Smokers
  1. Anniston, Alabama
  2. Anniston, Alabama
  3. Phoenix, Arizona
  4. Hot Springs, Arkansas
  5. Anaheim, California
  6. Los Angeles, California
  7. New Haven, Connecticut
  8. DeLand, Florida
  9. Gainesville, Florida
  10. Honolulu, Hawaii
  11. Honolulu, Hawaii
  12. Overland Park, Kansas
  13. Bardstown, Kentucky
  14. Lexington, Kentucky
  15. San Antonio, Texas
  16. Slough, Berkshire
12 Years+
Smoking CessationSmoking Cessation Study In Healthy Adolescent Smokers
  1. Ozark, Alabama
  2. Goodyear, Arizona
  3. Little Rock, Arkansas
  4. Anaheim, California
  5. La Habra, California
  6. National City, California
  7. Oakland, California
  8. Oceanside, California
  9. Aurora, Colorado
  10. Colorado Springs, Colorado
  11. Denver, Colorado
  12. New Haven, Connecticut
  13. New Haven, Connecticut
  14. New Haven, Connecticut
  15. DeLand, Florida
  16. Kissimmee, Florida
  17. Maitland, Florida
  18. Miami, Florida
  19. Miami, Florida
  20. North Bay Village, Florida
  21. Orange City, Florida
  22. Saint Petersburg, Florida
  23. Meridian, Idaho
  24. Meridian, Idaho
  25. Evansville, Indiana
  26. Indianapolis, Indiana
  27. Newburgh, Indiana
  28. Wichita, Kansas
  29. Bardstown, Kentucky
  30. Lexington, Kentucky
  31. Owensboro, Kentucky
  32. Owensboro, Kentucky
  33. New Orleans, Louisiana
  34. Watertown, Massachusetts
  35. Rochester Hills, Michigan
  36. Kansas City, Missouri
  37. O'Fallon, Missouri
  38. Saint Louis, Missouri
  39. Lincoln, Nebraska
  40. Raleigh, North Carolina
  41. Raleigh, North Carolina
  42. Wilmington, North Carolina
  43. Canton, Ohio
  44. Toledo, Ohio
  45. Oklahoma City, Oklahoma
  46. Charleston, South Carolina
  47. Mount Pleasant, South Carolina
  48. Dallas, Texas
  49. DeSoto, Texas
  50. Lake Jackson, Texas
  51. San Antonio, Texas
  52. San Antonio, Texas
  53. Richmond, Virginia
  54. Kirkland, Washington
  55. Richland, Washington
  56. Middleton, Wisconsin
  57. Ajax, Ontario
  58. New Market, Ontario
  59. Newmarket, Ontario
  60. Rustavi,
  61. Anyang-si, Gyeonggi-do
  62. Seongnam-si, Gyeonggi-do
  63. Suwon-si, Gyeonggi-do
  64. Daegu,
  65. Village Novoe Devyatkino, Leningrad Region
  66. Moscow,
  67. Murmansk,
  68. Novosibirsk,
  69. Saint-Petersburg,
  70. Saint-Petersburg,
  71. Saint-Petersburg,
  72. Saint-Petersburg,
  73. Saint-Petersburg,
  74. Samara,
  75. Kaohsiung City,
  76. New Taipei City,
  77. New Taipei City,
  78. Taichung city,
  79. Tainan,
  80. Taipei City,
12 Years+
Smoking CessationA Seven-Week Dose-Ranging Study of CP-526,555 Compared With Placebo and Zyban for Smoking Cessation
  1. Los Angeles, California
  2. Farmington, Connecticut
  3. Minneapolis, Minnesota
  4. Omaha, Nebraska
  5. New York, New York
  6. Portland, Oregon
  7. Morgantown, West Virginia
18 Years+
Advanced Information
Descriptive Information
Brief Title  ICMJE A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
Official Title  ICMJE A Multicenter, Open Label Study To Investigate The Feasibility And Efficacy Of A Smoking Cessation Program With Varenicline In Patients Undergoing Elective Surgery
Brief Summary It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior to surgery and in turn, whether this may lead to reductions in post-operative complication such as wound infections.
Detailed Description Recruitment to this study was terminated (on February 23, 2010) earlier than originally planned because recruitment was much slower than expected and therefore the study has already achieved its main objective of assessing the feasibility of conducting a larger study of similar design to investigate the efficacy of smoking cessation therapy in a pre-surgical setting. The decision to end recruitment to the trial was not based on any safety concerns.
Study Type  ICMJE Interventional
Study Phase  ICMJE Phase 4
Study Design  ICMJE Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Condition  ICMJE Smoking Cessation
Intervention  ICMJE Drug: Varenicline
Varenicline film coated tablets - escalating dose with maximum dose of 1mg bd
Other Name: Champix
Study Arms  ICMJE Smoking cessation tratment including varenicline
Intervention: Drug: Varenicline
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
Recruitment Information
Recruitment Status  ICMJE Completed
Actual Enrollment  ICMJE
 (submitted: March 29, 2010)
Original Estimated Enrollment  ICMJE
 (submitted: April 28, 2009)
Actual Study Completion Date  ICMJE July 2010
Actual Primary Completion Date July 2010   (Final data collection date for primary outcome measure)
Eligibility Criteria  ICMJE

Inclusion Criteria:

  • Smokers motivated to stop smoking scheduled for elective surgery

Exclusion Criteria:

  • Current or recent depression
  • Current or recent suicidal ideation
  • Uncontrolled or unstable clinically significant medical condition
Sex/Gender  ICMJE
Sexes Eligible for Study:All
Ages  ICMJE 18 Years and older   (Adult, Older Adult)
Accepts Healthy Volunteers  ICMJE No
Contacts  ICMJE Contact information is only displayed when the study is recruiting subjects
Listed Location Countries  ICMJE France,   Italy
Removed Location Countries  
Administrative Information
NCT Number  ICMJE NCT00889720
Other Study ID Numbers  ICMJE A3051113
Has Data Monitoring Committee No
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement  ICMJE Not Provided
Responsible Party Pfizer
Study Sponsor  ICMJE Pfizer
Collaborators  ICMJE Not Provided
Investigators  ICMJE
Study Director:Pfizer CT.gov Call CenterPfizer
PRS Account Pfizer
Verification Date July 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP