Impact Of Bacterial Resistance On Healthcare Costs For Hospitalized Patients With Complicated Intra-Abdominal Infections

Inclusion Criteria:

• A recorded primary diagnosis of a complicated intra-abdominal. infection (cIAI) and a procedure involving a laparotomy, laparoscopy, or percutaneous drainage of an intra-abdominal abscess The study will be a prospective, multi-centre, epidemiological study of patients (aged > 18 years) diagnosed with a complicated intra-abdominal infection AND who received a procedure involving laparotomy/laparoscopy or percutaneous drainage of an intra-abdominal abscess. cIAI's will include the following conditions/ diagnoses:
• Gastric ulcer with perforation;
• Gastric ulcer with hemorrhage and perforation;
• Duodenal ulcer with perforation;
• Duodenal ulcer with hemorrhage and perforation;
• Peptic ulcer with perforation;
• Peptic ulcer with hemorrhage and perforation;
• Gastrojejunal ulcer with perforation;
• Gastrojejunal ulcer with hemorrhage and perforation;
• Acute appendicitis with generalized peritonitis;
• Acute appendicitis with peritoneal abscess;
• Peritonitis;
• Abscess of intestine;
• Fistula of intestine, excluding rectum and anus;
• Ulceration of intestine;
• Perforation of intestine;
• Abscess of liver; or
• Acute cholecystitis with perforation.

The initial antibiotic regimen will be defined as all IV antibiotics newly received either on the day immediately prior to laparotomy or laparoscopy or percutaneous drainage of an intra-abdominal abscess, or on the day of these procedures, given that the use of these procedures prior to initiation of IV antibiotic regimens in complicated IAIs , which is increasingly common, is likely reflective of prophylaxis.

Exclusion Criteria:

• Patients not signing an informed consent form.
• Patients participating in another interventional study.