- A recorded primary diagnosis of a complicated intra-abdominal. infection (cIAI) and a
procedure involving a laparotomy, laparoscopy, or percutaneous drainage of an
intra-abdominal abscess The study will be a prospective, multi-centre, epidemiological
study of patients (aged > 18 years) diagnosed with a complicated intra-abdominal
infection AND who received a procedure involving laparotomy/laparoscopy or
percutaneous drainage of an intra-abdominal abscess. cIAI's will include the following
- Gastric ulcer with perforation;
- Gastric ulcer with hemorrhage and perforation;
- Duodenal ulcer with perforation;
- Duodenal ulcer with hemorrhage and perforation;
- Peptic ulcer with perforation;
- Peptic ulcer with hemorrhage and perforation;
- Gastrojejunal ulcer with perforation;
- Gastrojejunal ulcer with hemorrhage and perforation;
- Acute appendicitis with generalized peritonitis;
- Acute appendicitis with peritoneal abscess;
- Abscess of intestine;
- Fistula of intestine, excluding rectum and anus;
- Ulceration of intestine;
- Perforation of intestine;
- Abscess of liver; or
- Acute cholecystitis with perforation.
The initial antibiotic regimen will be defined as all IV antibiotics newly received either
on the day immediately prior to laparotomy or laparoscopy or percutaneous drainage of an
intra-abdominal abscess, or on the day of these procedures, given that the use of these
procedures prior to initiation of IV antibiotic regimens in complicated IAIs , which is
increasingly common, is likely reflective of prophylaxis.
- Patients not signing an informed consent form.
- Patients participating in another interventional study.