- Men or women of non-childbearing potential aged 18 to 50 years inclusive (healthy
young subjects) and > 65 years (healthy elderly subjects) at screening.
- Body mass index (BMI) in the range of 18 to 32 kg/m2 and body weight >= 50 kg.
- Presence or history of any disorder that may prevent the successful completion of the
- Any surgical or medical condition that may interfere with the absorption,
distribution, metabolism, or excretion of the investigational drug or placebo.