Eligibility criteria
Condition
Non-Small Cell Lung Cancer
Sex
Females and Males
Age
18 + years
Inclusion criteria
Show details
- histologically proven diagnosis of Non-Small Cell Lung Cancer (NSCLC) that is locally
advanced or metastatic and of the adenocarcinoma subtype (including mixed
adenosquamous histology)
- evident disease progression by Response Evaluation Criterion in Solid Tumors (RECIST)
after at least one but no more than 2 chemotherapy regimens for advanced disease
- tumors must have measurable disease as per RECIST
Exclusion criteria
Show details
- known interstitial lung disease
- prior treatment with an agent that is known or proposed to be active by action on EGFR
tyrosine kinase or c-Met/HGF (Phase 2 Portion)