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A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis

Last updated on March 14, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Birmingham, Alabama, 35205 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Rheumatoid Arthritis
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Subject must have a diagnosis of rheumatoid arthritis based on the American College of
Rheumatology Association

- The subject has active disease at both Screening and Baseline, as defined:

- ≥4 joints tender or painful on motion, AND

- ≥4 joints swollen;

- The subject must have at least one knee, one elbow, one wrist or two
metacarpophalangeal joints with active synovitis suitable for biopsy by the shaver
technique

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- No arthroscopy should have been performed in the past 3 months in the same joint that
is to be biopsied in this study.

- No intra-articular steroids should have been injected in the joint to be biopsied in
this study in the previous 3 months.

- Subjects with evidence of hematopoietic disorders or evidence of hemoglobin levels 9.0 gm/dL or hematocrit baseline synovial biopsy.

- An absolute white blood cell (WBC) count of neutrophil count of prior to baseline synovial biopsy.

- Thrombocytopenia, as defined by a platelet count screening visit or within the 3 months prior to baseline synovial biopsy.

- Estimated GFR less than 40 ml/min based on Cockcroft Gault calculation .

NCT00976599
Pfizer
Completed
A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

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FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now