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Effects Of Eplerenone On Serum Aldesterone And Plasma Renin Activity

Last updated on February 20, 2019

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Study Location
Pfizer Investigational Site
Miami, Florida, 33143 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Healthy Volunteers
Sex
Male
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-55 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight >50 kg (110 lbs)

- Subjects who are willing and able to comply with scheduled visits, treatment plan,
laboratory tests, and other study procedures.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Evidence or history of clinically significant disease

- Subjects with a supine BP greater than or equal to 140 mm Hg systolic or greater than
or equal to 90 mm Hg diastolic or single measurement, as described in the protocol

- Blood donation of approximately 1 pint (500 mL) within 56 days prior to dosing

- History of sensitivity to eplerenone, spironolactone or related compounds.

- Serum potassium >5.0 mEq/L at screening or Day 0

NCT00990223
Pfizer
Completed
Effects Of Eplerenone On Serum Aldesterone And Plasma Renin Activity

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Pfizer Clinical Trials Contact Center

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[email protected]

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Contact a representative by phone, email, or visiting the study website. Please see the references below:

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Pfizer Clinical Trials Contact Center

1-800-718-1021

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Contact

[email protected]

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