- Patients with interstitial cystitis/ painful bladder syndrome for more than 6 months
with moderate to severe pain and a micturition frequency greater than 7 per day.
- Patients who have been on stable oral medicines for interstitial cystitis/ painful
bladder syndrome for at least 3 months. Other therapies might need to be stopped.
- Patients on certain recent treatments for interstitial cystitis/ painful bladder
syndrome.
- Body mass index (BMI) of >39 kg/m2.
- History of allergic or anaphylactic reaction to a therapeutic or diagnostic monoclonal
antibody or IgG-fusion protein.
- Patients with peripheral neuropathy.
- Patients with Type I or type II diabetes mellitus who have an HbA1c > 8.0%.