Bioequivalence Study Comparing Linezolid 600 Mg Oral Suspension With 600 Mg Tablet In Chinese Healthy Male Subjects

• Drug: Linezolid
  
  1. Linezolid OS 600 MG
  2. Linezolid Tablet 600 MG
  Other Name: Zyvox
• Drug: Linezolid
  
  1. Linezolid Tablet 600 MG
  2. Linezolid OS 600 MG
  Other Name: Zyvox

• Group 1
  
  Subjects will accept Linezolid OS 600 MG first, after 4 days wash-out, then will accept Linezolid tablet 600 MG.
  Intervention: Drug: Linezolid
• Group 2
  
  Subjects will accept Linezolid tablet 600 MG first, after 4 days wash-out, then will accept Linezolid OS 600 MG.
  Intervention: Drug: Linezolid

Inclusion Criteria:

• Healthy volunteers.
• 18-40 years old, male.
• BMI 19-24kg/m2.

Exclusion Criteria:

• Alcohol, drug, smoke user.
• Sensitive to oxazolidinones antibiotics class drug or heparin.
• Severe medical or psychiatric condition or laboratory abnormality.
• Blood donation.
• 12-ECG abnormal.
• Treatment with study drug; clinically significant.