- Adult male or female
- Written informed consent
- Diagnosis of chronic pancreatitis based on imaging studies
- Persistent abdominal pain due to chronic pancreatitis
- Qualifying pain score during the pre-treatment period
- Willing to comply with study visit schedule and study requirements including for women
of child-bearing potential or male patients with female partners of child-bearing
potential, the use of 2 forms of birth control
- Pregnant women, lactating mothers, women suspected of being pregnant and women who
wish to become pregnant during the course of the study
- Chronic pancreatitis as a complication of pancreatic cancer or acute pancreatic duct
obstruction
- Pancreatic surgery, lithotripsy or endoscopist decompression within 3 months
- History of alcoholism (within 1 year of screening) or concurrent alcohol abuse
- History of cancer in the past years
- Significant cardiac disease within 6 months
- History, diagnosis or signs and symptoms of significant neurologic disease
- Disqualifying laboratory values including Hepatitis B or C, HIV and drug test
- Other medical condition that may interfere with study endpoints or safety of the
patient as determined by the Investigator
- Known history of rheumatoid arthritis
- Avascular necrosis of the bone
- History of trauma to a major joint Evidence of osteoarthritis