- Healthy male and/or female of non-child bearing potential subjects between the ages of
18 and 55 years, inclusive (Healthy is defined as no clinically relevant abnormalities
identified by a detailed medical history, full physical examination, including blood
pressure and pulse rate measurement, 12-lead ECG and clinical laboratory tests).
- Body Mass Index (BMI) of 17.5 to 30.5 kg/m^2; and a total body weight >50 kg (110
- Subjects with evidence of disease, conditions affecting drug absorption, treatment
with other investigational drug within 30 days, history of regular alcohol
consumption, and use of prescription , nonprescription drugs and dietary supplement
within 7 days, and blood donation of 500 mL within 56 days.