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Bosutinib For Autosomal Dominant Polycystic Kidney Disease

Last updated on March 14, 2019

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Study Location
Southwest Kidney Institute, PLC
Phoenix, Arizona, 85004 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Autosomal Dominant Polycystic Kidney
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-50 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Males and females, 18 to 50 years old at the time of consent.

- Documented diagnosis of ADPKD (PKD-1 or PKD-2 genotypes allowed).

- Total kidney volume ≥ 750 cc, as measured by centrally evaluated MRI.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- eGFR

- Uncontrolled hypertension (defined as systolic blood pressure ?140 or diastolic blood
pressure ?90 mm Hg).

- Any previous exposure to the bosutinib test article or receipt of other polycystic
kidney disease (PKD) therapies.

NCT01233869
Pfizer
Completed
Bosutinib For Autosomal Dominant Polycystic Kidney Disease

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