A Study Comparing the Drug Exposure in Humans After Administration of a 50 mg Tablet of Sertraline Hydrochloride as Compared to a 50 mg Capsule of Sertraline Hydrochloride Under Fasted (Nonfed) Conditions

• Drug: sertraline hydrochloride
  
  50 mg capsule, single-dose
  Other Name: Zoloft
• Drug: sertraline hydrochloride
  
  50 mg tablet, single-dose
  Other Name: Zoloft

• Active Comparator: Sertraline 50 mg capsules
  
  Intervention: Drug: sertraline hydrochloride
• Active Comparator: Sertraline 50 mg tablet
  
  Intervention: Drug: sertraline hydrochloride

Inclusion Criteria:

• Healthy male and/or female subjects between the ages of 21 and 55 years, inclusive (Healthy is defined as no clinically relevant abnormalities identified by a detailed medical history, full physical examination, including blood pressure and pulse rate measurement, 12-lead ECG and clinical laboratory tests).
• Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight >45 kg (99 lbs).

Exclusion Criteria:

• Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease (including drug allergies, but excluding untreated, asymptomatic, seasonal allergies at time of dosing).
• Any condition possibly affecting drug absorption (eg, gastrectomy)