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Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects

Last updated on February 20, 2019

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Study Location
Pfizer Investigational Site
New Haven, Connecticut, 06510 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Healthy
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
21-45 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Healthy male and/or female subjects between the ages of 21 and 45 years, inclusive.
Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight >50 kg (110 lbs).
(Healthy is defined as no clinically relevant abnormalities identified by a detailed
medical history, full physical examination, including blood pressure and pulse rate
measurement, 12 lead ECG and clinical laboratory tests).

- Right handed as determined by handedness questionnaire.

- Able to read and write English as a primary language.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Female subjects who are pregnant or breastfeeding.

- Any evidence of significant psychosis-like symptoms.

- Known sensitivity to ketamine.

NCT01244880
Pfizer
Terminated
Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects

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