CP-690-550 Ointment For Chronic Plaque Psoriasis

• Drug: CP-690,550 Ointment 1
  
  2% CP-690,550 Ointment 1 twice daily for 4 weeks
• Drug: Vehicle 1
  
  Vehicle 1 twice daily for 4 weeks
• Drug: CP-690,550 Ointment 2
  
  2% CP-690,550 Ointment 2 twice daily for 4 weeks
• Drug: Vehicle 2
  
  Vehicle 2 twice daily for 4 weeks

• Experimental: Treatment Group A
  
  Intervention: Drug: CP-690,550 Ointment 1
• Placebo Comparator: Treatment Group B
  
  Intervention: Drug: Vehicle 1
• Experimental: Treatment Group C
  
  Intervention: Drug: CP-690,550 Ointment 2
• Placebo Comparator: Treatment Group D
  
  Intervention: Drug: Vehicle 2

Inclusion Criteria:

• Mild to moderate chronic plaque psoriasis (psoriasis vulgaris), with the duration of at least 6 months;
• A target plaque of at least 9 sq. cm.

Exclusion Criteria:

• Demonstrates "rebound" or "flare" of chronic plaque psoriasis;
• Non plaque form of psoriasis;
• Currently have or history of psoriatic arthritis;
• Current drug induced psoriasis;
• Currently on systemic therapy or was on systemic therapy for psoriasis within the previous 6 months;
• Currently on phototherapy for psoriasis or was on phototherapy within the previous 3 months