- Male and/or female subjects between the ages of 18 and 60 years;
- Body Mass Index (BMI) of >25.0 kg/m2 and
- Subjects must have a historical diagnosis of T2DM in accordance with the ADA
guidelines;
- Subjects who have been on well-tolerated and stable doses of metformin
- Recent evidence (6 months prior to screening) or history of unstable major organ
disease;
- Diagnosis of Type 1 diabetes mellitus;
- Current medical history of myocardial infarction, unstable angina, or history of
stroke (including TIA) within 6 months prior to Screening;
- Treatment with thiazolidinediones (TZDs), or subcutaneously administered antidiabetic
agents;