- Healthy male and/or female subjects between the ages of 18 and 55 years,Females must
be of non-childbearing potential. Body mass index of 17.5 to 30.5 kg/m2.
- Subjects who are willing and able to comply with all scheduled visits, treatment plan,
laboratory tests, and other study procedures.
- Serum potassium >5 mEq/L at screening.
- Impaired kidney function (estimated GFR eplerenone, spironolactone, or related compounds.