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A Study Of PF-05190457 In Healthy Volunteers And Type-2 Diabetic Patients

Last updated on March 14, 2019

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Study Location
Pfizer Investigational Site
New Haven, Connecticut, 06511 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Type 2 Diabetes Mellitus
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-55 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Healthy males and females of non-childbearing potential between ages of 18 and 55
years, BMI of 18.5 to 30.5 kg/m^2, and weight between 50 and 100 kg, inclusive.

- Type 2 diabetic males and females of non-childbearing potential between ages of 18 and
55 years, BMI of 18.5 to 40.0 kg/m^2, weight between 50 and 150 kg, and HbA1c of
7.0-10.0%, inclusive.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Evidence or history of clinically significant hematological, renal, endocrine,
pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or
allergic disease.

- Additionally, type 2 diabetic patients who have history of diabetic complications with
significant end-organ damage or pharmacologic treatment for diabetes in addition to
metformin.

NCT01372163
Pfizer
Terminated
A Study Of PF-05190457 In Healthy Volunteers And Type-2 Diabetic Patients

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[email protected]

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