Systematic Review And Meta-Analysis Of Psoriasis Treatments.
NCT01425138
Last updated date
ABOUT THIS STUDY
This project involved a systematic literature review of published trials of treatments for
moderate-to-severe plaque psoriasis. Data was extracted from the publications on various
psoriasis endpoints including the Physician Global Assessment (PGA), Dermatology Life Quality
Index (DLQI), and Short-Form 36 (SF-36). A traditional meta-analysis and a mixed treatment
comparison was conducted on the extracted data.
FOR MORE INFORMATION
Contact a representative by phone, email, or visiting the study website. Please see the references below:
By phone
Pfizer Clinical Trials Contact Center
1-800-718-1021
Eligibility Criteria
condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Psoriasis
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
Adult Trials: 18+ Years
18 + years
Inclusion Criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details
- Randomized controlled clinical trials of treatments for moderate-to-severe plaque psoriasis.
- Trials had to evaluate at least one of the following: Physician's Global Assessment (PGA), Dermatology Life Quality Index (DLQI) and/or the Short-Form 36 (SF-36).
Exclusion Criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details
Observational studies
- Trials that did not report the Physician's Global Assessment (PGA),
- Dermatology Life Quality Index (DLQI) or the Short-Form 36 (SF-36).
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Advanced Information
| Descriptive Information | ||||
|---|---|---|---|---|
| Brief Title | Systematic Review And Meta-Analysis Of Psoriasis Treatments. | |||
| Official Title | Biologic And Non-biologic Systemic Treatments For Moderate To Severe Plaque Psoriasis: A Systematic Review & Meta-Analysis | |||
| Brief Summary | This project involved a systematic literature review of published trials of treatments for moderate-to-severe plaque psoriasis. Data was extracted from the publications on various psoriasis endpoints including the Physician Global Assessment (PGA), Dermatology Life Quality Index (DLQI), and Short-Form 36 (SF-36). A traditional meta-analysis and a mixed treatment comparison was conducted on the extracted data. | |||
| Detailed Description | This project involved a systematic literature review of published trials of treatments for moderate-to-severe plaque psoriasis. Data was extracted from the publications on various psoriasis endpoints including the Physician Global Assessment (PGA), Dermatology Life Quality Index (DLQI), and Short-Form 36 (SF-36). A traditional meta-analysis and a mixed treatment comparison was conducted on the extracted data. We included all published randomized controlled trials of treatments for moderate-to-severe psoriasis that met the study inclusion criteria. | |||
| Study Type | Observational | |||
| Study Design | Observational Model: Other Time Perspective: Retrospective | |||
| Target Follow-Up Duration | Not Provided | |||
| Biospecimen | Not Provided | |||
| Sampling Method | Non-Probability Sample | |||
| Study Population | Moderate-to-severe plaque psoriasis published trials. | |||
| Condition | Psoriasis | |||
| Intervention | Not Provided | |||
| Study Groups/Cohorts | Psoriasis
Published data on moderate-to-severe plaque psoriasis. | |||
| Publications * | Not Provided | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. | ||||
| Recruitment Information | ||||
| Recruitment Status | Completed | |||
| Actual Enrollment | 1 | |||
| Original Estimated Enrollment | 0 | |||
| Actual Study Completion Date | June 2011 | |||
| Actual Primary Completion Date | June 2011 (Final data collection date for primary outcome measure) | |||
| Eligibility Criteria | Inclusion Criteria:
Exclusion Criteria: Observational studies
| |||
| Sex/Gender |
| |||
| Ages | 18 Years and older (Adult, Older Adult) | |||
| Accepts Healthy Volunteers | No | |||
| Contacts | Contact information is only displayed when the study is recruiting subjects | |||
| Listed Location Countries | Not Provided | |||
| Removed Location Countries | ||||
| Administrative Information | ||||
| NCT Number | NCT01425138 | |||
| Other Study ID Numbers | A3921142 | |||
| Has Data Monitoring Committee | No | |||
| U.S. FDA-regulated Product | Not Provided | |||
| IPD Sharing Statement | Not Provided | |||
| Responsible Party | Pfizer | |||
| Study Sponsor | Pfizer | |||
| Collaborators | University of Connecticut School of Pharmacy and Hartford Hospital | |||
| Investigators |
| |||
| PRS Account | Pfizer | |||
| Verification Date | November 2018 | |||