You are here

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Last updated on March 14, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Charleroi, , 6000 Belgium
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Early Breast Cancer (Phase 2), Advanced Breast Cancer (Phase 1b)
Sex
Female
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Phase 1 - Postmenopausal women with diagnosis of breast cancer, metastatic disease or
locally advanced disease / Estrogen Receptor positive and HER-2 negative / candidate
to receive Letrozole

- Phase 2 - Postmenopausal women with newly diagnosed primary breast cancer / Estrogen
Receptor positive and HER-2 negative / Ki-67 levels >10% positive cells

- Phase 1 & 2 - Glucose control, adequate bone marrow, liver, renal, and cardiac
function

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Inflammatory carcinoma / Prior therapy with an agent active on PI3K and/or mTOR /
Significant gastrointestinal abnormalities, which may impair intake, transit or
absorption of the study drugs / Current or anticipated need for food or drugs that are
known inhibitors or inducers of CYP3A4

NCT01430585
Pfizer
Terminated
Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

Try a new search

Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now