- Japanese healthy postmenopausal women
- History or current evidence of thrombophlebitis, thromboembolic disorders, or any
- History or presence of malignancy or estrogen-dependent neoplasia. Subjects with a
documented history of any malignancy, except for basal or squamous cell carcinoma of
skin, which has been treated and fully resolved for a minimal 5 years.
- History or presence of benign or malignant liver tumor that developed during the use
of oral contraceptives or other estrogen-containing products.