Eligibility criteria
Condition
Multiple Myeloma
Sex
Females and Males
Age
18 + years
Inclusion criteria
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- Previously treated multiple myeloma with a quantifiable serum (M spike ≥ 1 g/dL)
and/or urine (≥ 200 mg/24-hr) paraprotein
- Adequate bone marrow, renal, liver and cardiac function
- Eastern Cooperative Oncology Group [ECOG] performance status less than or equal to 2
Exclusion criteria
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- Prior allogeneic stem cell transplant (alloSCT)
- Myelosuppressive chemotherapy or immunotherapy within 3 weeks prior to treatment with
CP-751,871
- Prior organ allograft
- Concurrent use of insulin, oral hypoglycemic medication, growth hormone (GH), or
growth hormone inhibitors
- Female patients who are pregnant or lactating