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Effect of Linezolid on Ex Vivo Neutrophil and Monocyte Function in Healthy Males

Last updated on March 15, 2019

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Study Location
Pfizer Investigational Site
New Haven, Connecticut, 06511 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Gram Positive Infection
Sex
Male
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
20-45 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Healthy male subjects between the ages of 20 and 45 years, inclusive (Healthy is
defined as no clinically relevant abnormalities identified by a detailed medical
history, full physical examination, including blood pressure and pulse rate
measurement and clinical laboratory tests).

- Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight >50 kg (110 lbs).

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Any condition possibly affecting drug absorption (eg, gastrectomy).

- Subject who had a bacterial/viral infection within 2 weeks prior to the first dose of
study medication.

- Subjects with current or prior neutropenia (eg,

NCT01544673
Pfizer
Completed
Effect of Linezolid on Ex Vivo Neutrophil and Monocyte Function in Healthy Males

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