You are here

To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)

Last updated on March 14, 2019

FOR MORE INFORMATION
Study Location
Research Site
London, , United Kingdom
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Complicated Infection, Bacterial Infections
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-130 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Provision of signed and dated, written informed consent prior to any study specific
procedures

- Healthy young male and female volunteers aged 18 to 45 years (inclusive) and healthy
elderly volunteers aged 65 or older (Part C) with suitable veins for cannulation or
repeated venipuncture

- Have a body mass index (BMI) between 19 and 30 kg/m2

- Be able to understand and willing to comply with study procedures, restrictions, and
requirements, as judged by the PI

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- History of any clinically significant disease or disorder which, in the opinion of the
PI, may either put the volunteer at risk because of participation in the study, or
influence the results or the volunteer's ability to participate in the study

- History or presence of gastrointestinal, hepatic, or renal disease, or any other
condition known to interfere with absorption, distribution, metabolism, or excretion
of drugs

- Known history of severe allergy to betalactam and/or L-arginine

- History of severe allergy/hypersensitivity or ongoing clinically important
allergy/hypersensitivity, as judged by the PI or history of hypersensitivity to drugs
with a similar chemical structure or class to ATM or AVI

- Any clinically significant illness, medical/surgical procedure, or trauma within 4
weeks prior to the first administration of IP

NCT01689207
Pfizer
Completed
To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

Try a new search

Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now