- Medically stable kidney transplant patients 6 or more months after transplantation.
- Subjects must be on mycophenolate mofetil 1-2 gm daily
- In Cohort 3 (and 4, if conducted) in Stage 1 and the expanded cohort in Stage 2,
subjects must be on a calcineurin inhibitor-free regimen.
- Any rejection episodes in the preceding 3 months.
- Treated with Thymoglobulin or OKT3 for acute rejection in the past 6 months.