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A 6-Week Study Of PF-05175157 In Type 2 Diabetes Mellitus

Last updated on March 15, 2019

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Study Location
Profil Institute for Clinical Research, Inc.
Chula Vista, California, 91911 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Type 2 Diabetes Mellitus
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-65 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Subjects who have been diagnosed with type 2 diabetes mellitus by a medical
professional according to the American Diabetes Association guidelines.

- Hemoglobin A1c of ≥7 and ≤10.0% in subjects who are metformin-naive or have not taken
metformin for 2 months or Hemoglobin A1c of ≥6.5 and ≤9.5% in subjects who are
metformin-naïve and are taking SU or DPP-IVi which is washed off or taking metformin
and are willing to discontinue metformin in a 8-week washout period.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Evidence or history of clinically significant hematological, renal, endocrine (other
than T2DM and hypothyroidism), gastrointestinal, cardiovascular, pulmonary, hepatic,
psychiatric or neurologic disease.

- A waist circumference which makes fitting imto the bore of the MR scanner impossible.

Subjects with history of dry eye, known ocular or systemic disease that affect the sclera
or cornea.

NCT01792635
Pfizer
Terminated
A 6-Week Study Of PF-05175157 In Type 2 Diabetes Mellitus

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