You are here

Effect Of PF-06305591 On Capsaicin And Capsaicin/Heat-Induced Neurogenic Flare

Last updated on February 20, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Brussels, , B-1070 Belgium
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Healthy
Sex
Male
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-55 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Healthy male Caucasian subjects with skin type I-III inclusive (Fitzpatrick Scale),
between the ages of 18 and 55 years, inclusive (Healthy is defined as no clinically
relevant abnormalities identified by a detailed medical history, full physical
examination, including blood pressure and pulse rate measurement, 12 lead ECG and
clinical laboratory tests).

- An informed consent document signed and dated by the subject.

- Subjects must have a distance from base of scaphoid to antecubital fossa equal of
greater to 26 cm on their forearms.

- Subjects who demonstrate a capsaicin -mediated neurogenic flare with a value >200 on
the arbitrary Laser Doppler output at any of the time points 30, 40, 50 or 60 minutes
following administration of capsaicin at Screening.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Evidence or history of clinically significant hematological (ie, abnormalities due to
prolonged exposure to altitude), renal), endocrine or dismetabolic, pulmonary,
gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic or pain condition,
dermatological or allergic disease (including drug allergies, but excluding untreated,
asymptomatic, seasonal allergies at time of dosing).

- Subjects with scars or tattoos on the forearms, or with evidence of sunburn, or
excessively hairy volar forearms.

- History of febrile illness within 5 days prior to dosing.

NCT01797796
Pfizer
Completed
Effect Of PF-06305591 On Capsaicin And Capsaicin/Heat-Induced Neurogenic Flare

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

Try a new search

Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now