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Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease

Last updated on March 14, 2019

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Study Location
Centre d'Investigation Clinique (CIC)/ Institut du Cerveau et de la Möelle Epinière (ICM)
Paris Cedex 13, , 75651 France
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Huntington's Disease
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-70 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Must have a diagnosis of Huntington's Disease

- a CAG repeat expansion equal or great than 39

- a Unified Huntington Disease Rating Scale (UHDRS) Total Motor Score equal or greater
than 5 and less than 60

- a UHDRS Total Functional Capacity equal or greater than 9

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Subjects with evidence or history of severe acute or chronic medical condition or
laboratory abnormality, or significant neurological disorder other than HD.

- Treatment with any antipsychotic medication within 5 weeks of enrollment

NCT01806896
Pfizer
Completed
Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease

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[email protected]

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