- Male and Female subjects in good general health, aged 18 to 65 years.
- Subjects should meet IHS diagnostic criteria for migraine with or without aura.
- Based on past history, subjects should expect to suffer at least one acute attack of
migraine with or without aura, each 6 weeks
- Known coronary-artery disease, clinically significant arrhythmia, heart failure, or
uncontrolled hypertension.
- Pregnant or lactating women.
- Clinically significant electrocardiogram abnormalities at screening.