- Healthy male and female (non-childbearing potential). Healthy is defined as no
clinically relevant abnormalities identified by a detailed medical history, full
physical examination including blood pressure, pulse, ECG, and laboratory testing.
- Evidence or history of clinically significant infectious, hematological, renal,
endocrine, pulmonary gastrointestinal, cardiovascular, hepatic psychiatric,
neurologic, autoimmune, or allergic disease.