Healthy male and/or female subjects of non-childbearing potential between the ages of 18
and 55 years
Female subjects of non childbearing potential that meet at least one of the following
criteria:
Achieved postmenopausal status, defined as: cessation of regular menses for at least 12
consecutive months with no alternative pathological or physiological cause; and have a
serum follicle stimulating hormone (FSH) level confirming the postmenopausal status;
- Have undergone a documented hysterectomy and/or bilateral oophorectomy;
- Have medically confirmed ovarian failure.
Evidence or history of clinically significant hematological, renal, endocrine, pulmonary,
gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease
(including drug allergies, but excluding untreated, asymptomatic, seasonal allergies at
time of dosing).
Any condition possibly affecting drug absorption .