- Female subjects of non-childbearing potential; Healthy subjects identified by a
detailed medical history, full physical examination including blood pressure and pulse
rate measurement, 12-lead ECG or clinical laboratory test.
- A positive urine drug screen, urine cotinine test or alcohol breath test.
- Treatment with an investigational drug within 30 days or 5 half-lives preceding the
first dose of study medication.
- Use of prescription or nonprescription drugs and dietary supplements within 7 days or
5 half-lives prior to the first dose of study medication. All antacid agents must be
discontinued 28 days prior to the first dose of study medication.