- Personally signed and dated informed consent document.
- Renal function calculated by the Cockcroft Gault equation: normal function (CLcr >=90
mL/min), mild: CLcr >=60 mL/min and =30 mL/min and mL/min, severe: CLcr
- Subjects with normal renal function matched for age, weight, gender and race to
subjects in impaired renal function groups.
- Any condition possibly affecting drug absorption.
- Renal allograft recipients.