Eligibility criteria
Condition
Healthy
Sex
Females and Males
Age
18-55 years
Inclusion criteria
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- Healthy male subjects and female subjects of non childbearing potential between the
ages of 18 and 55 years, inclusive.
- Body Mass Index (BMI) of 17.5 to 30.5 kg/m2; and a total body weight >50 kg (110 lbs).
Exclusion criteria
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- Subjects who received within 7 days prior to the first dose of study medication or are
likely to receive during the study any moderate strong inhibitors of CYP3A4, eg,
itraconazole, erythromycin, ketoconazole, protease inhibitors, verapamil, or
diltiazem.
- Subjects who received within 28 days or are likely to receive during the study
inducers of CYP3A4, eg rifampin.