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A Study Of PF-05280014 Or Trastuzumab Plus Taxotere® And Carboplatin In HER2 Positive Breast Cancer In The Neoadjuvant Setting (REFLECTIONS B327-04)

Last updated on March 14, 2019

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Study Location
Compassionate Cancer Care Medical Group, Inc.
Fountain Valley, California, 92708 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Early Breast Cancer
Sex
Female
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Histologically confirmed HER2 overexpressing invasive breast cancer.

- Plan for definitive surgical resection of breast tumor (i.e., lumpectomy or
mastectomy, and sentinel node (SN) biopsy or axillary lymph node dissection (ALND).

- Plan for neoadjuvant chemotherapy.

- Measurable disease in the breast after diagnostic biopsy, defined as longest diameter
≥ 2.0 cm.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Bilateral breast cancer.

- Inflammatory breast cancer.

- Presence of known distant metastases.

- Received prior treatment, including chemotherapy, endocrine therapy, biologic therapy,
radiation or surgery with the exception of diagnostic biopsy for primary breast
cancer.

NCT02187744
Pfizer
Completed
A Study Of PF-05280014 Or Trastuzumab Plus Taxotere® And Carboplatin In HER2 Positive Breast Cancer In The Neoadjuvant Setting (REFLECTIONS B327-04)

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