- Healthy males and females between the ages of 70 and 80.
- Subjects must have BMI of 17.5 to 32 kg/m2 and total body weight > 110 pounds.
- Acceptable screening MRI and PET scans that pass quality control requirements.
- Co-morbid diagnosis of clinically documented Alzheimer's disease; - Significant
- MMSE (mini mental state examination) score <26