A Study To Evaluate The Effect Of Food On The Behavior of Tofacitinib Modified Release 22 Milligram Tablets In Healthy Volunteers

• Drug: Tofacitinib MR 22 mg (Fed)
  
  A single dose of tofacitinib modified release 22 mg tablet after receiving the standard FDA high-fat/high-calorie meal
• Drug: Tofacitinib MR 22 mg (Fasted)
  
  A single dose of tofacitinib modified release 22 mg tablet after an overnight fast of 10 hours

• Experimental: Tofacitinib MR 22 mg Fed
  
  Single dose of tofacitinib MR 22 mg administered under fed conditions
  Intervention: Drug: Tofacitinib MR 22 mg (Fed)
• Experimental: Tofacitinib MR 22 mg Fasted
  
  Single dose of tofacitinib MR 22 mg administered under fasted conditions
  Intervention: Drug: Tofacitinib MR 22 mg (Fasted)

Inclusion Criteria:

• Healthy male volunteers and/or healthy female volunteers of non-childbearing potential who are 18 to 55 years of age;
• Healthy volunteers with no evidence of active or latent or inadequately treated tuberculosis.

Exclusion Criteria:

• Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease;
• Clinically significant infections within the past 3 months