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Study in Healthy Subjects to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06687234

Last updated on March 14, 2019

FOR MORE INFORMATION
Study Location
Pfizer Clinical Research Unit
Brussels, , B-1070 Belgium
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Healthy
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-55 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Healthy females of non childbearing potential and healthy males

- No evidence of active or latent or inadequately treated infection with Mycobacterium
tuberculosis (TB)

- Ability to personally sign and date the informed consent document and able to comply
with schedule of activities

- For Single Dose Cohort 7 only, Japanese subjects must have four biological Japanese
grandparents born in Japan.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Evidence or history of clinically significant health concerns

- Treatment with an investigational drug within 30 days

- Exposure to any live vaccines within 28 days prior to investigational product
administration.

- History of drug and/ or alcohol abuse and tobacco use equivalent of 5 cigarettes per
day.

- Known history of infection with hepatitis B virus, hepatitis C virus, or human
immunodeficiency virus

- Pregnant female subjects

- History of sensitivity to heparin

- Unwilling or unable to comply with the Lifestyle Guidelines as stated in the protocol

NCT02711462
Pfizer
Terminated
Study in Healthy Subjects to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06687234

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[email protected]

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Pfizer Clinical Trials Contact Center

1-800-718-1021

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