- Healthy male and/or female subjects of non childbearing potential.
- Body Mass Index (BMI) of >=25 kg/m2; and a total body weight >50 kg
- Subjects with liver fat >=6% and
- Evidence or history of clinically significant hematological, renal, endocrine,
pulmonary,gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or
allergic disease (including drug allergies, but excluding untreated, asymptomatic,
seasonal allergies at time of dosing).