Determining and Addressing Adherence to the NCCN Guidelines for Chronic Phase CML

The overall goal of this program is to test a novel behavior change and education intervention to improve physician adherence to the NCCN guidelines and best practice recommendations for chronic-phase chronic myeloid leukemia (CP-CML) at four oncology practices across Colorado.

Key Objective 1: Establish a one-year baseline rate of adherence to NCCN guidelines for qPCR monitoring of BCR-ABL1 in the peripheral blood of CP-CML patients treated at four oncology practices across the state of Colorado.

Key Objective 2: Implement and assess an interactive behavior modification and education intervention designed to improve provider adherence to NCCN guidelines for qPCR monitoring of BCR-ABL1 and increase provider knowledge of treatment guidelines about TKI choice and ways providers can address the problem of patient adherence to TKI medications.