Celebrex (celecoxib capsules), a prescription nonsteroidal anti-inflammatory, is a treatment for the signs and symptoms of osteoarthritis and rheumatoid arthritis, and in the U.S. and certain EU countries for the management of acute pain in adults. Celebrex is supported by continued educational and promotional efforts highlighting its efficacy and safety profile for appropriate patients.
One of the most studied arthritis pain medicines available today
Enbrel (etanercept) is used to treat moderate to severe rheumatoid arthritis, moderately to severely active polyarticular juvenile rheumatoid arthritis, psoriatic arthritis, adult chronic moderate to severe plaque psoriasis and ankylosing spondylitis, a type of arthritis affecting the spine. A biologic that can be self-injected, Enbrel was the first biologic approved for moderate-to-severe rheumatoid arthritis, and has more than a decade of continuous safety data in patients with rheumatoid arthritis.
No. 1 most prescribed biologic by rheumatologists
Lipitor (atorvastatin) is prescribed to treat elevated LDL-cholesterol levels in the blood. In 2011, it was the most widely used branded prescription treatment for lowering cholesterol and the best-selling prescription pharmaceutical product of any kind in the world. Lipitor is proven to reduce the risk of heart attack, stroke and other cardiovascular events in patients with certain cardiovascular risk factors or with heart disease. Despite losing exclusivity in many markets, including the U.S. in 2011, Lipitor continues to be one of Pfizer's most important products.
Studied in more than 400 ongoing or completed trials, including more than 80,000 patients
Lyrica (pregabalin) is indicated for the management of fibromyalgia, neuropathic pain associated with diabetic peripheral neuropathy (diabetic nerve pain), post-herpetic neuralgia (pain after shingles) and as an adjunctive therapy for adults with partial onset seizures in the U.S., and for neuropathic pain, adjunctive treatment of epilepsy and general anxiety disorder in certain countries outside the U.S.
First approved treatment for fibromyalgia in the U.S.
Norvasc (amlodipine besylate), despite facing generic competition since 2007, remains the world's most prescribed brand name pharmaceutical for high blood pressure. Pfizer makes and distributes generic versions of Norvasc through the Established Products/Emerging Markets Business Unit and continues to make the branded version widely available.
No. 1 most prescribed branded medicine for high blood pressure
Prevnar 13/Prevenar 13 Pediatric
Prevnar 13/Prevenar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) is a 13-valent pneumococcal conjugate vaccine. First introduced in 2009, it is now the world's top-selling pneumococcal vaccine, and is approved for infants and young children in more than 110 countries. It was recently approved in the U.S. and Europe and more than 10 other countries for use in adults 50 years and older.
World's top-selling pneumococcal vaccine
Pristiq (desvenlafaxine) is used to treat major depressive disorder in adults, and is believed to work on two chemicals in the brain, serotonin and norepinephrine. In contrast to many other antidepressants that must be started at a low dose and titrated up to a therapeutic dose, Pristiq patients can start at a dose proven to relieve depression symptoms: 50 mg, one pill, once a day. In addition, Pristiq does not undergo CYP2D6 metabolism in the liver, thereby reducing the risks of pharmacokinetic drug-drug interaction with other medications that do need to be metabolized through this important enzyme system.
Once-a day, 50 mg dose, proven to relieve depression symptoms
Sutent (sunitinib malate) is used by oncologists to treat advanced renal cell carcinoma, including metastatic renal cell carcinoma (mRCC), gastrointestinal stromal tumors after disease progression on, or intolerance to, imatinib mesylate, and advanced pancreatic neuroendocrine tumors. The third indication was approved in late 2010 in the EU and in 2011 in the U.S. Sutent's efficacy in first-line mRCC includes two-year survival data, the first time that overall survival of two years has been seen in the treatment of advanced kidney cancer.
Most-prescribed oral mRCC therapy in the U.S.
Viagra (sildenafil citrate) is the No. 1 prescribed treatment for erectile dysfunction (ED) in the world and one of the world's most recognized pharmaceutical brands. Introduced in 1998, Viagra is backed by more than 13 years of patient experience, and has been shown to effectively treat ED in men who have concomitant health issues such as hypertension, depression and diabetes.
No. 1 prescribed treatment for erectile dysfunction in the world
Zyvox (linezolid) is the world's best-selling branded agent for the treatment of certain serious complicated skin and nosocomial pneumonia infections caused by gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Zyvox works against MRSA by a unique mechanism of action, minimizing the potential for cross-resistance. Available in both oral and intravenous forms, and approved for adults and children, Zyvox offers doctors considerable flexibility in the transition of patients from hospital settings to home or other convalescent care.
World's best-selling branded agent for the treatment of MRSA