Our solutions help patients and health care providers manage chronic, costly conditions, and are designed to improve outcomes and overall health. Through leadership in areas such as the management of pain and heart disease, our medicines treat conditions that account for a large and growing portion of the world's health care costs. Our pipeline includes medicines with potential in women's health, pain, cardiovascular and metabolic diseases, respiratory diseases, and Alzheimer's disease.
Eliquis (apixaban) gained approval to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation in the U.S., the 27 countries in the European Union, Canada, and Japan, and is under review in other countries. Eliquis, an oral Factor Xa inhibitor anticoagulant, has demonstrated superior risk reductions versus warfarin in three key outcomes of stroke and systemic embolism, major bleeding and all-cause death in patients with nonvalvular atrial fibrillation. In 2007, Pfizer and Bristol-Myers Squibb entered into a worldwide collaboration to develop and commercialize this oral anticoagulant, which was discovered by Bristol-Myers Squibb.
Lyrica (pregabalin) capsules CV received a new indication in the U.S. for the management of neuropathic pain associated with spinal cord injury. This is the fifth indication approved for Lyrica. Core indications for Lyrica are fibromyalgia and diabetic peripheral neuropathy, and Lyrica is the first indication approved for the management of neuropathic pain associated with spinal cord injury in the U.S.
Lyrica received regulatory approval in Japan for the additional indication of pain associated with fibromyalgia.
Integrated Health, Pfizer's new approach to identifying innovative ways to partner with payers, providers and employers to improve patient outcomes, launched its first two products focused on the employer health and wellness market: KEAS, an online platform designed to engage employees around healthy behaviors; and the American Health Strategies Project, a tool designed to help demonstrate the costs of chronic diseases and highlight potential interventions to reduce costs and improve employee health outcomes.