Clinical Development Scientist, Director (Inflammation and Immunology)
- United States - Massachusetts - Cambridge
POSITION SUMMARY
You will provide medical and scientific leadership for one or more complex clinical trials within our Inflammation and Immunology portfolio. You will be responsible for the clinical integrity, scientific quality, and patient safety of clinical studies, partnering closely with Clinical Operations and cross-functional stakeholders to deliver high-quality, efficient trials.
You will play a critical role in protocol development, study execution, data interpretation, and risk management, while serving as the primary clinical contact for investigators and internal study teams.
In addition, you will drive the integration of AI-enabled and advanced analytics solutions to transform clinical development workflows, improving speed, efficiency, and decision-making across the clinical trial lifecycle.
KEY RESPONSIBILITIES
Core Clinical Leadership
Lead the clinical execution of one or more medium- to high-complexity clinical studies
Provide clinical leadership in protocol design and development
Partner with Clinical Operations and cross-functional teams
Oversee clinical data review and safety surveillance
Serve as the primary clinical contact for stakeholders
AI-Enabled Clinical Development & Innovation
Lead identification and implementation of AI/ML and advanced analytics tools to optimize clinical trial design and execution]
Partner with Data Science, Digital, and Technology teams to translate AI use cases into scalable workflows
Champion adoption of innovative tools across study teams
Clinical Strategy and Deliverables
Contribute to clinical documents (protocols, CSRs, regulatory submissions)
Support risk management and safety review
Incorporate AI-derived insights and data-driven approaches into clinical strategy and regulatory deliverables where appropriate
MINIMUM QUALIFICATIONS
PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in the biopharmaceutical industry, OR
MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in the biopharmaceutical industry OR
BA/BS in a relevant Science discipline and minimum of 8 years Clinical Research experience in the biopharmaceutical industry
Deep knowledge of clinical development, ICH/GCP, global regulatory requirements, and safety management
Experience leading complex clinical studies and working effectively in cross‑functional, global teams
Strong written and verbal communication skills, with experience engaging internal and external stakeholders
Experience applying AI, machine learning, or advanced analytics in clinical development or research (e.g., protocol design and optimization, site selection and feasibility assessment, query management and workflow automation, data cleaning, anomaly detection, and signal identification, safety risk prediction and proactive mitigation)
Familiarity with AI-enabled use cases including protocol design, recruitment optimization, data review, and safety prediction
Experience partnering with data science or digital teams
Understanding of data governance and AI considerations in GxP environments
PREFERRED QUALIFICATONS
Advanced degree or professional certification in a scientific, medical, or healthcare related discipline
Experience in respiratory and/or dermatology therapeutic areas
Experience with real-world data, digital endpoints, or innovative clinical technologies
COMPETENCIES FOR SUCCESS
Promotes innovation and challenges the status quo
Embraces evolving technologies
Demonstrates intellectual curiosity and proactively explores emerging tools (including AI) to continuously improve and transform clinical development workflows
Demonstrates digital and data fluency, with ability to leverage AI tools responsibly and effectively
Balances innovation with patient safety, regulatory compliance, and scientific rigor
Demonstrates strong judgment and decision-making
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
None
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Occasional travel may be required
Relocation support available
WORK LOCATION ASSIGNMENT: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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Medical
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Research & Development
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
With an unwavering commitment to innovation, we use a multidisciplinary approach that blends scientific expertise, cutting-edge technologies, and strategic collaborations, igniting a powerful engine that propels groundbreaking discoveries into life-saving treatments for patients in need.
Through our relentless pursuit of progress, we envision a future where cutting-edge medicines pave the way to healthier, happier lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)