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Product Pipeline

Our Medicines in Development

Our priority is researching and developing products and treatments that will benefit patients around the world. And from specialized efforts in biosimilars and rare disease to oncology and vaccines, we are committed to developing medical solutions that will matter most to the people we serve.

Key Innovative Programs in Registration / Phase 3

  • Bavencio (avelumab): Non-Small Cell Lung Cancer, Gastric Cancer, Ovarian Cancer, Renal Cell Carcinoma, Squamous Cell Carcinoma of the Head and Neck, Urothelial Cancer (in collaboration w/ Merck KGaA)
  • glasdegib (PF-04449913) (SMO Inhibitor): Acute Myeloid Leukemia
  • Ibrance (palbociclib): High Risk Early Breast Cancer, Early Breast Cancer in Adjuvant Setting, HER2+ Breast Cancer
  • JAK1 Inhibitor: Atopic Dermatitis
  • lorlatinib (PF-06463922) (ALK/ROS1): Non-Small Cell Lung Cancer
  • Prophylactic Vaccine for Clostridium difficile Infection
  • Rivipansel: Vaso-Occlusive Crisis Associated with Sickle Cell Disease
  • somatrogon (PF-06836922): Adult Growth Hormone Deficiency, Pediatric Growth Hormone Deficiency (in collaboration w/ OPKO)
  • talazoparib (MDV3800): Breast Cancer, Prostate Cancer
  • Tanezumab: OA Signs and Symptoms, Chronic Low Back Pain, Cancer Pain
  • Vyndaqel (tafamidis meglumine): Cardiomyopathy
  • Xeljanz® (tofacitinib): Ulcerative Colitis
  • Xtandi (enzalutamide): Prostate Cancer

Key Biosimilars Programs in Registration / Phase 3

  • A potential biosimilar to Humira® (adalimumab): Rheumatoid Arthritis
  • A potential biosimilar to Avastin® (bevacizumab): Non-Small Cell Lung Cancer
  • A potential biosimilar to Epogen® and Procrit® (epoetin alfa): Anemia
  • A potential biosimilar to Neupogen® (filgrastim): Neutropenia in patients undergoing cancer chemotherapy
  • A potential biosimilar to Rituxan®/MabThera (rituximab): Follicular Lymphoma
  • A potential biosimilar to Herceptin® (trastuzumab): Breast Cancer

Key Programs in Phase 2

  • ACC Inhibitor: Non-Alcoholic Steatohepatitis (NASH)
  • Coagulation Factor IX (F9): Hemophilia
  • Dekavil (IL-10 Agonist): Rheumatoid Arthritis
  • domagrozumab (PF-06252616) (Myostatin Inhibitor): Duchenne Muscular Dystrophy
  • IRAK4 Inhibitor: Rheumatoid Arthritis
  • JAK3 Inhibitor: Alopecia Areata, Crohn’s Disease, Rheumatoid Arthritis, Ulcerative Colitis
  • KHK Inhibitor: Non-Alcoholic Steatohepatitis (NASH)
  • Next Generation Pneumococcal Conjugate Prophylactic Vaccine for Invasive and Non-Invasive Pneumococcal Infections
  • Prophylactic Vaccine for Staphylococcus aureus Infection
  • TYK2/JAK1 Inhibitor: Alopecia Areata, Crohn’s Disease, Psoriasis, Ulcerative Colitis


Rituxan® is a registered U.S. trademark of Biogen MA Inc.; MabThera is a trademark of F. Hoffmann La Roche AG; Avastin® and Herceptin® are registered U.S. trademarks of Genentech, Inc.; Humira® is a registered U.S. trademark of Abbvie Biotechnology Ltd.; Epogen® is a registered U.S. trademark of Amgen Inc.; Neupogen® is a registered U.S. trademarks of Amgen Inc.; Procrit® is a registered U.S. trademark of Johnson & Johnson